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N-substituted 4,5(3)-diphenyl-3(5)-pyrazoleamines with antipyretic, antiarrhythmic, hypotensive and other activities
- Source :
- Farmaco (Societa chimica italiana : 1989). 48(7)
- Publication Year :
- 1993
-
Abstract
- The synthesis of N-substituted 4,5(3)-diphenyl-3(5)-pyrazoleamines by reaction of N-substituted 3-oxo-2,3-diphenylpropane-carbothioamides with hydrazine is described. Some compounds showed remarkable antipyretic, antiarrhythmic and hypotensive activity in rats, as well as weak antiinflammatory, analgesic and in vitro platelet antiaggregating activity.
Details
- ISSN :
- 0014827X
- Volume :
- 48
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Farmaco (Societa chimica italiana : 1989)
- Accession number :
- edsair.pmid.dedup....8b92d35bcbac8553d81f8752e97a3088