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Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults
- Source :
- BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019), BMC Cancer
- Publication Year :
- 2019
- Publisher :
- BMC, 2019.
-
Abstract
- Background It remains controversial whether weight change could influence the risks of colorectal cancer (CRC) and mortality. This study aimed to quantify the associations between full-spectrum changes in body mass index (BMI) and the risks of colorectal cancer (CRC) incidence, cancer-related and all-cause mortality among midlife to elder population. Methods A total of 81,388 participants who were free of cancer and aged 55 to 74 years from the Prostate, Lung, Colorectal, and Ovarian (PLCO) screening program were involved. The percentage change of BMI was calculated as (BMI in 2006 - BMI at baseline)/BMI at baseline, and was categorized into nine groups: decrease (≥ 15.0%, 10.0–14.9%, 5.0–9.9%, 2.5–4.9%), stable (decrease/increase
- Subjects :
- Adult
Male
Colorectal cancer risk
lcsh:RC254-282
Body Mass Index
Longitudinal association
Risk Factors
Cause of Death
Humans
Multicenter Studies as Topic
Longitudinal Studies
Mortality
Early Detection of Cancer
Aged
Randomized Controlled Trials as Topic
Incidence
Age Factors
Middle Aged
Prognosis
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
BMI change
Survival Rate
Older adults
Female
Colorectal Neoplasms
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 14712407
- Volume :
- 19
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Cancer
- Accession number :
- edsair.pmid.dedup....c0e2e76ad89cf47e4100744a4e9fd4cd