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Auto-immune spondylodiscitis associated with collagen induced arthritis in rats: high field MRI findings

Authors :
Pierre GILLET
Fener, P.
Escanyé, J.
Walker, P.
Bannwarth, B.
Jouzeau, J.
Drelon, E.
Floquet, J.
Netter, P.
Robert, J.
Laboratoire de Physiopathologie et Pharmacologie Articulaire (CNRS URA 1288)
Service de Rhumatologie [CHRU Nancy]
Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)
Service de Médecine Nucléaire [Nancy]
Service d’Anatomie Pathologique [CHRU Nancy]
Source :
HAL, Agents and actions. Supplements, Agents and actions. Supplements, 1991, pp.185-9

Abstract

International audience; The spinal involvement of the tail was studied in Wistar Furth rats immunized with bovine native type II collagen. Focal caudal autoimmune spondylodiscitis occurred 5 weeks after sensitization, as assessed histopathologically. High field Magnetic Resonance Imaging (MRI) was useful in depicting these caudal abnormalities that were related to juxta-diskal enthesitis. The occurrence of such inflammatory enthesopathies could serve as an experimental approach for physiopathological and therapeutical studies of spondylarthropathies.

Details

ISSN :
03790363
Database :
OpenAIRE
Journal :
HAL, Agents and actions. Supplements, Agents and actions. Supplements, 1991, pp.185-9
Accession number :
edsair.pmid.dedup....cefbf343797731a40944c8e9e3ef33f4