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Lower-Limb Lymphedema after Sentinel Lymph Node Biopsy in Cervical Cancer Patients
- Source :
- Cancers, Volume 13, Issue 10, Cancers, Vol 13, Iss 2360, p 2360 (2021), Dipòsit Digital de la UB, Universidad de Barcelona
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- Background: To prospectively assess LLL incidence among cervical cancer patients treated by uterine surgery complemented by SLN biopsy, without PLND. Methods: A prospective study in 150 patients with stage IA1–IB2 cervical cancer treated by uterine surgery with bilateral SLN biopsy. Objective LLL assessments, based on limb volume increase (LVI) between pre- and postoperative measurements, and subjective patient-perceived swelling were conducted in six-month periods over 24-months post-surgery. Results: The cumulative incidence of LLL at 24 months was 17.3% for mild LLL (LVI 10–19%), 9.2% for moderate LLL (LVI 20–39%), while only one patient (0.7%) developed severe LLL (LVI &gt<br />40%). The median interval to LLL onset was nine months. Transient edema resolving without intervention within six months was reported in an additional 22% of patients. Subjective LLL was reported by 10.7% of patients, though only a weak and partial correlation between subjective-report and objective-LVI was found. No risk factor directly related to LLL development was identified. Conclusions: The replacement of standard PLND by bilateral SLN biopsy in the surgical treatment of cervical cancer does not eliminate the risk of mild to moderate LLL, which develops irrespective of the number of SLN removed.
- Subjects :
- PELVIC LYMPHADENECTOMY
lower limb lymphedema
GYNECOLOGIC CANCER
cervical cancer
Cervical vertebrae
Biopsy
RADICAL SURGERY
Article
Lymphedema
LOWER-EXTREMITY LYMPHEDEMA
Càncer
sentinel lymph node biopsy
CIRCUMFLEX ILIAC NODES
QUESTIONNAIRE GCLQ
RC254-282
Cancer
COMPLICATIONS
Science & Technology
pelvic lymphadenectomy
Vèrtebres cervicals
ENDOMETRIAL
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
GOG 244-THE LYMPHEDEMA
Oncology
Limfoedema
RISK-FACTORS
Biòpsia
Life Sciences & Biomedicine
Subjects
Details
- Language :
- English
- ISSN :
- 20726694
- Database :
- OpenAIRE
- Journal :
- Cancers
- Accession number :
- edsair.pmid.dedup....f9f26e4084142ac791f8666bd5ebcc97
- Full Text :
- https://doi.org/10.3390/cancers13102360