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A multi-scale approach to the physics of ion beam cancer therapy

Authors :
Solov'yov, A. V.
Surdutovich, E.
Scifoni, E.
Mishustin, I.
Greiner, W.
Publication Year :
2008

Abstract

We propose a multi-scale approach to understanding physics related to the ion/proton-beam cancer therapy and calculation of the probability of the DNA damage as a result of irradiation of patients with energetic (up to 430 MeV/u) ions. This approach is inclusive with respect to different scales starting from the long scale defined by the ion stopping followed by a smaller scale defined by secondary electrons and radicals ending with the shortest scale defined by interactions of secondaries with the DNA. We present calculations of the probabilities of single and double strand breaks of the DNA and suggest a way of further elaboration of such calculations.<br />Comment: submitted to RADAM2008 proceedings. 8 pages,5 Figures, class files for AIP included

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.0807.2597
Document Type :
Working Paper
Full Text :
https://doi.org/10.1063/1.3058987