Parameter estimation for computationally intensive nonlinear regression with an application to climate modeling

Nonlinear regression is a useful statistical tool, relating observed data and a nonlinear function of unknown parameters. When the parameter-dependent nonlinear function is computationally intensive, a straightforward regression analysis by maximum likelihood is not feasible. The method presented in this paper proposes to construct a faster running surrogate for such a computationally intensive nonlinear function, and to use it in a related nonlinear statistical model that accounts for the uncertainty associated with this surrogate. A pivotal quantity in the Earth's climate system is the climate sensitivity: the change in global temperature due to doubling of atmospheric $\mathrm{CO}_2$ concentrations. This, along with other climate parameters, are estimated by applying the statistical method developed in this paper, where the computationally intensive nonlinear function is the MIT 2D climate model.
Comment: Published in at http://dx.doi.org/10.1214/08-AOAS210 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)