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GBM Volumetry using the 3D Slicer Medical Image Computing Platform
- Source :
- Sci. Rep. 3, 1364, 2013
- Publication Year :
- 2013
-
Abstract
- Volumetric change in glioblastoma multiforme (GBM) over time is a critical factor in treatment decisions. Typically, the tumor volume is computed on a slice-by-slice basis using MRI scans obtained at regular intervals. (3D)Slicer - a free platform for biomedical research - provides an alternative to this manual slice-by-slice segmentation process, which is significantly faster and requires less user interaction. In this study, 4 physicians segmented GBMs in 10 patients, once using the competitive region-growing based GrowCut segmentation module of Slicer, and once purely by drawing boundaries completely manually on a slice-by-slice basis. Furthermore, we provide a variability analysis for three physicians for 12 GBMs. The time required for GrowCut segmentation was on an average 61% of the time required for a pure manual segmentation. A comparison of Slicer-based segmentation with manual slice-by-slice segmentation resulted in a Dice Similarity Coefficient of 88.43 +/- 5.23% and a Hausdorff Distance of 2.32 +/- 5.23 mm.<br />Comment: 7 pages, 6 figures, 2 tables, 1 equation, 43 references
- Subjects :
- Computer Science - Computer Vision and Pattern Recognition
Subjects
Details
- Database :
- arXiv
- Journal :
- Sci. Rep. 3, 1364, 2013
- Publication Type :
- Report
- Accession number :
- edsarx.1303.0964
- Document Type :
- Working Paper
- Full Text :
- https://doi.org/10.1038/srep01364