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Ferroptosis as a Biological Phase Transition I: avascular and vascular tumor growth

Authors :
Nieto-Villar, J. M.
Mansilla, R.
Publication Year :
2021

Abstract

Herewith we discuss a network model of the ferroptosis avascular and vascular tumor growth based on our previous proposed framework. Chiefly, ferroptosis should be viewed as a first order phase transition characterized by a supercritical Andronov Hopf bifurcation, with the emergence of limit cycle. The increase of the population of the oxidized PUFA fragments, take as the control parameter, involves an inverse Feigenbaum, (a cascade of saddle foci Shilnikov's bifurcations) scenario, which results in the stabilization of the dynamics and in a decrease of complexity.<br />Comment: 13 pages, 3 figures

Details

Database :
arXiv
Publication Type :
Report
Accession number :
edsarx.2109.02476
Document Type :
Working Paper