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123-I ioflupane (Datscan®) presynaptic nigrostriatal imaging in patients with movement disorders

Authors :
Angel Soriano Castrejón
Ana María García Vicente
Montserrat Cortés Romera
Julia Vaamonde Cano
Sonia Rodado Marina
Victor Manuel Poblete García
Sebastián Ruiz Solís
María del Prado Talavera Rubio
Source :
Brazilian Archives of Biology and Technology, Vol 48, Iss spe2, Pp 115-126 (2005)
Publication Year :
2005
Publisher :
Instituto de Tecnologia do Paraná (Tecpar), 2005.

Abstract

123-I Ioflupane (Datscan®) presynaptic imaging has been shown to have a significant utility in the assessment of patients with movement disorders 123-I Ioflupane SPECT is able to distinguish between Parkinson’s disease (PD) and other forms of parkinsonism without degeneration of the nigrostriatal pathway, including a common movement disorder such as essential tremor, and to assess disease progression in PD and other neurodegenerative disorders involving the substantia nigra.A imagem pré-sináptica através de 123-I Ioflupane (Datscan®) tem mostrado um papel significante na avaliação de pacientes com distúrbios do movimento. 123-I Ioflupane SPECT é capaz de distinguir entre Mal de Parkinson (MP) e outras formas de parkinsonismo sem degenerações da via nigroestriatal incluindo um distúrbio comum de movimento parecido com o tremor essencial e para medir a evolução da doença no Mal de Parkinson e outros distúrbios neurodegenerativos envolvendo a substantia nigra.

Details

Language :
English
ISSN :
15168913 and 16784324
Volume :
48
Issue :
spe2
Database :
Directory of Open Access Journals
Journal :
Brazilian Archives of Biology and Technology
Publication Type :
Academic Journal
Accession number :
edsdoj.002877ac60b6420ea4a8596c204b9e25
Document Type :
article
Full Text :
https://doi.org/10.1590/S1516-89132005000700017