Clinical observation on the efficacy and safety of skin care product containing artemisia naphtha in individuals with sensitive skin

Objective To evaluate the safety and efficacy of skin care product containing artemisia naphtha in individuals with sensitive skin. Methods A single-center and self-controlled (before and after application) clinical trial was conducted in 31 subjects with sensitive skin. Test product was applied to the face of the subjects twice daily for 4 weeks. Measurement of physiological function, VISIA-CR photography and lactic acid test were carried out on the skin before and on the days 7,14,28 of the trial. 16S rRNA gene sequencing technology was used to analyze the microecological diversity of the skin surface meanwhile physician and subject' self-assessments were performed. Results Physician assessment scores for erythema were decreased at all three follow-up visits (P