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Prospective effects of cholecalciferol supplementation on irisin levels in sedentary postmenopausal women: A pilot study
- Source :
- Journal of Clinical & Translational Endocrinology, Vol 34, Iss , Pp 100324- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- Introduction: In postmenopausal women, vitamin D deficiency has been associated with disability, low muscle mass and fractures. Irisin is an important myokine that may contribute to the maintenance of muscle and bone density. Vitamin D is associated with the growth and function of muscle tissue through interactions between the vitamin D receptor and PGC-1α and activation of p38/MAPK (mitogen-activated protein kinase) in muscle, a mechanism similar to irisin action. The aim of this pilot study was to evaluate the effects of cholecalciferol supplementation on serum irisin levels in sedentary postmenopausal women with hypovitaminosis D (25(OH)D
Details
- Language :
- English
- ISSN :
- 22146237
- Volume :
- 34
- Issue :
- 100324-
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Clinical & Translational Endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.037ca4701970412e9aaa63abc1c633bc
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jcte.2023.100324