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Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

Authors :
Qi Zhao
Feng Wang
Yan-Xing Chen
Shifu Chen
Yi-Chen Yao
Zhao-Lei Zeng
Teng-Jia Jiang
Ying-Nan Wang
Chen-Yi Wu
Ying Jing
You-Sheng Huang
Jing Zhang
Zi-Xian Wang
Ming-Ming He
Heng-Ying Pu
Zong-Jiong Mai
Qi-Nian Wu
Renwen Long
Xiaoni Zhang
Tanxiao Huang
Mingyan Xu
Miao-Zheng Qiu
Hui-Yan Luo
Yu-Hong Li
Dong-Shen Zhang
Wei-Hua Jia
Gong Chen
Pei-Rong Ding
Li-Ren Li
Zheng-Hai Lu
Zhi-Zhong Pan
Rui-Hua Xu
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The ChangKang (Heathy Bowel) project was established to collect molecular and clinical information of a thousand Chinese colorectal cancer patients. Here, the authors present the genomic landscape of the ChangKang cohort and find a subgroup of patients defined by abnormal mitochondrial copy numbers.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.0548bf4a574cba8d5b0964a7e38b91
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30062-8