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Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

Authors :
Anne Karine Lagendijk
Guillermo A. Gomez
Sungmin Baek
Daniel Hesselson
William E. Hughes
Scott Paterson
Daniel E. Conway
Heinz-Georg Belting
Markus Affolter
Kelly A. Smith
Martin A. Schwartz
Alpha S. Yap
Benjamin M. Hogan
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.05f4c034d6774bbe95030ef2e8d3c537
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-01325-6