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Bilateral Breast Ochronosis: a Case Report
- Source :
- JPRAS Open, Vol 30, Iss , Pp 23-28 (2021)
- Publication Year :
- 2021
- Publisher :
- Elsevier, 2021.
-
Abstract
- ABSTRACT: Ochronosis is a syndrome characterized by bluish black discoloration due to the deposition of polymerized products of homogentisic acid (HGA) in the connective tissues. The endogenous variety (alkaptonuria), is a rare autosomal recessive metabolic disorder. The disorder is manifested by deficiency of the enzyme homogentisate 1,2-dioxygenase. The characteristic of the condition is a triad of pigmentation of skin, cartilage, and sclera; ochronotic arthropathies and homogentisic aciduria (resulting in darkening of urine). More rarely, it may affect the breast. This rare and interesting case of a woman with ochronosis of both breasts and chest wall, prompted us to write this case report.
- Subjects :
- Ochronosis
Alkaptonuria
Homogentisic acid
Breast ochronosis
Mastectomy
Surgery
RD1-811
Subjects
Details
- Language :
- English
- ISSN :
- 23525878
- Volume :
- 30
- Issue :
- 23-28
- Database :
- Directory of Open Access Journals
- Journal :
- JPRAS Open
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.06cabf0603c142f4a4a1622d3102325d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jpra.2021.06.005