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Imaging Inflammation – From Whole Body Imaging to Cellular Resolution

Authors :
Tuula Peñate Medina
Jan Philip Kolb
Gereon Hüttmann
Robert Huber
Oula Peñate Medina
Linh Ha
Patricia Ulloa
Naomi Larsen
Arianna Ferrari
Magdalena Rafecas
Mark Ellrichmann
Mariya S. Pravdivtseva
Mariia Anikeeva
Jana Humbert
Marcus Both
Jennifer E. Hundt
Jan-Bernd Hövener
Source :
Frontiers in Immunology, Vol 12 (2021)
Publication Year :
2021
Publisher :
Frontiers Media S.A., 2021.

Abstract

Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging modalities and evaluated the recent findings on preclinical and clinical inflammation imaging. The focus has been on the feasibility of imaging to aid in inflammation precision medicine, and the key challenges and opportunities of the imaging modalities are presented. Some examples of the current usage in clinics/close to clinics have been brought out as an example. This review evaluates the future prospects of the imaging technologies for clinical applications in precision medicine from the pre-clinical development point of view.

Details

Language :
English
ISSN :
16643224
Volume :
12
Database :
Directory of Open Access Journals
Journal :
Frontiers in Immunology
Publication Type :
Academic Journal
Accession number :
edsdoj.0816e60bf23c465aa04f3e40d520ffb1
Document Type :
article
Full Text :
https://doi.org/10.3389/fimmu.2021.692222