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Serological responses and vaccine effectiveness for extended COVID-19 vaccine schedules in England

Authors :
Gayatri Amirthalingam
Jamie Lopez Bernal
Nick J. Andrews
Heather Whitaker
Charlotte Gower
Julia Stowe
Elise Tessier
Sathyavani Subbarao
Georgina Ireland
Frances Baawuah
Ezra Linley
Lenesha Warrener
Michelle O’Brien
Corinne Whillock
Paul Moss
Shamez N. Ladhani
Kevin E. Brown
Mary E. Ramsay
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

The UK extended the interval until the second COVID-19 vaccine dose up to 12 weeks. Here, the authors show in a cohort of 750 participants aged 50–89 years that the extended schedule results in higher antibody titers and estimate a higher vaccine effectiveness for the extended schedule.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.08652fe260e04b43aa30fee89b6a203d
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27410-5