Short‐Term Effects of Different Transcatheter Edge‐to‐Edge Devices on Mitral Valve Geometry

Background Short‐term effects on mitral valve (MV) anatomy after transcatheter edge‐to‐edge repair using the PASCAL system remain unknown. Precise quantification might allow for an advanced analysis of predictors for mean transmitral gradients. Methods and Results Consecutive patients undergoing transcatheter edge‐to‐edge repair for secondary mitral regurgitation using PASCAL or MitraClip systems were included. Quantification of short‐term MV changes throughout the cardiac cycle was performed using peri‐interventional 3‐dimensional MV images. Predictors for mean transmitral gradients were identified in univariable and multivariable regression analysis. Long‐term results were described during 1‐year follow‐up. A total of 100 patients undergoing transcatheter edge‐to‐edge repair using PASCAL (n=50) or MitraClip systems (n=50) were included. Significant reductions of anterior‐posterior diameter, annular circumference, and area throughout the cardiac cycle were found in both cohorts (P