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Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish

Authors :
Xiao-Ning Cheng
Ming Shao
Ji-Tong Li
Yan-Fei Wang
Jing Qi
Zhi-Gang Xu
De-Li Shi
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Gastrulation is an early morphogenic event driven by coordinated asymmetric/polarised cell movements. Here, the authors show in zebrafish that Lurap1, a protein that interacts with Dishevelled, regulates Wnt and planar cell polarity, coordinating centriole positioning during convergence and extension.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.0b3ddf5bf8db41e0a668d2ad794611c2
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-01552-x