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Emerin increase in regenerating muscle fibers
- Source :
- European Journal of Histochemistry, Vol 49, Iss 4 (2009)
- Publication Year :
- 2009
- Publisher :
- PAGEPress Publications, 2009.
-
Abstract
- The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with respect to normal mature myofibers. This finding suggests an involvement of emerin during the muscle fiber regeneration process, in analogy with its reported involvement in muscle cell differentiation in vitro. The impairment of skeletal muscle physiological regeneration or reorganization could be a possible pathogenetic mechanism for Emery Dreifuss muscular dystrophy.
- Subjects :
- Biology (General)
QH301-705.5
Subjects
Details
- Language :
- English
- ISSN :
- 1121760X and 20388306
- Volume :
- 49
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- European Journal of Histochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0cab392b631c42bb94f801fe8d7d389c
- Document Type :
- article
- Full Text :
- https://doi.org/10.4081/963