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Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex

Authors :
Marion Kuhn
Elias Wolf
Jonathan G. Maier
Florian Mainberger
Bernd Feige
Hanna Schmid
Jan Bürklin
Sarah Maywald
Volker Mall
Nikolai H. Jung
Janine Reis
Kai Spiegelhalder
Stefan Klöppel
Annette Sterr
Anne Eckert
Dieter Riemann
Claus Normann
Christoph Nissen
Source :
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Publication Year :
2016
Publisher :
Nature Portfolio, 2016.

Abstract

Sleep deprivation is believed to lead to homeostatic increases in synaptic strength and reduced inducibility of associative LTP, based mainly on findings from animal studies. Here, Kuhn et al. demonstrate similar sleep-dependent synaptic plasticity changes in humans along with altered plasma BDNF levels.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.0e1dc550214448b9b2178f6b9c19a22a
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms12455