Back to Search
Start Over
Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- SIRT1 is a NAD+-dependent deacetylase whose functions have been linked to organismal longevity, aging and metabolism. Here, Matsui and colleagues show that neuronal SIRT1 can affect nutrient-related dietary choice in mice, and this effect is mediated by FGF21 signalling and oxytocin.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0e6908642176438fbd24e41a6c8e07f1
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-07033-z