Extracellular fluid excess linked to reduced choroidal vascularity index in patients with chronic kidney disease

Abstract Extracellular fluid (ECF) excess is common in patients with chronic kidney disease (CKD). This study (involving 284 patients with CKD) explored the association between choroidal vascularity index (CVI) and ECF excess. We categorised patients into three groups based on extracellular water/total body water: normal, mildly overhydrated, and severely overhydrated. The more severe ECF status was associated with a lower CVI after adjustment (B = − 0.902, p = 0.001). In non-diabetic patients, both vascular luminal (LA, p