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Construction of 3-amino-9-ethylcarbazole scaffold for multifunctional applications: Chemosensor for copper(II) ions along with antibacterial, antioxidant and anti-inflammatory activity
- Source :
- Results in Chemistry, Vol 6, Iss , Pp 101141- (2023)
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- This work describes the fabrication of a carbazole derivative 1 namely (E)-5-(diethylamino)-2-((9-ethyl-9H-carbazol-3-yl)imino)methyl)phenol(1) based colorimetric probe for the selective detection of copper (II) ions. The as-prepared carbazole derivative was characterized using various spectral techniques including UV–visible absorption, Emission, FT-IR, 1H NMR, 13C NMR and mass spectra. The colorimetric chemosensing potential of the synthesized carbazole derivative 1 to detect Cu2+ ions in a solution of different cations at different emission wavelengths based on photo-induced electron transfer (PET) mechanism was undertaken. In addition, the probe 1 showed significant DPPH scavenging activity. Antimicrobial and anti-inflammatory activities of the carbazole derivative 1 were also assessed. The selectivity of probe 1 towards Cu2+ ions could be exploited to reduce copper induced toxicity.
Details
- Language :
- English
- ISSN :
- 22117156
- Volume :
- 6
- Issue :
- 101141-
- Database :
- Directory of Open Access Journals
- Journal :
- Results in Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0fb0d754f14b45bd2c35a52dd5859e
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.rechem.2023.101141