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A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Authors :
Yuqi Zhang
Jing Fang
Shuyue Ye
Yan Zhao
Anna Wang
Qiulian Mao
Chaoxiang Cui
Yali Feng
Jiachen Li
Sunao Li
Mingyang Zhang
Haibin Shi
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Abnormal levels of intracellular hydrogen sulphide (H2S) have been associated with different pathological conditions, including cancer. Here the authors report the design of a H2S-responsive and -depleting nanoplatform that, combined with NIR-II photodynamic properties, can be used for H2S imaging and cancer therapy.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.10118a05739d4269a671ec0f0a04bb93
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29284-7