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Twelve-month specific IgG response to SARS-CoV-2 receptor-binding domain among COVID-19 convalescent plasma donors in Wuhan

Authors :
Cesheng Li
Ding Yu
Xiao Wu
Hong Liang
Zhijun Zhou
Yong Xie
Taojing Li
Junzheng Wu
Fengping Lu
Lu Feng
Min Mao
Lianzhen Lin
Huanhuan Guo
Shenglan Yue
Feifei Wang
Yan Peng
Yong Hu
Zejun Wang
Jianhong Yu
Yong Zhang
Jia Lu
Haoran Ning
Huichuan Yang
Daoxing Fu
Yanlin He
Dongbo Zhou
Tao Du
Kai Duan
Demei Dong
Kun Deng
Xia Zou
Ya Zhang
Rong Zhou
Yang Gao
Xinxin Zhang
Xiaoming Yang
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

COVID-19 pandemic is a global health risk, but our understanding on the induced durable immunity remains scarce. Here the authors assess antibody responses in 869 convalescent COVID-19 patients to find that specific antibody titers reduce with time, and the RBD-IgG positive rate exceed 70% at 12 month post diagnosis, with male and older patients showing stronger responses.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1065a88af3e648ed97acfd3b3383177a
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-24230-5