Back to Search
Start Over
Non-peptide compounds from Kronopolites svenhedini (Verhoeff) and their antitumor and iNOS inhibitory activities
- Source :
- Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 789-799 (2023)
- Publication Year :
- 2023
- Publisher :
- Beilstein-Institut, 2023.
-
Abstract
- Six new compounds, including a tetralone 1, two xanthones 2 and 3, a flavan derivative 4, and two nor-diterpenoids 7 and 8, accompanied by two known flavan derivatives 5 and 6 and a known olefine acid (9) were isolated from whole bodies of Kronopolites svenhedini (Verhoeff). The structures of the new compounds were determined by 1D and 2D nuclear magnetic resonance (NMR) and other spectroscopic methods, as well as computational methods. Selected compounds were evaluated for their biological properties against a mouse pancreatic cancer cell line and inhibitory effects on iNOS and COX-2 in RAW264.7 cells.
Details
- Language :
- English
- ISSN :
- 18605397
- Volume :
- 19
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Beilstein Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.12c370a61c3543348e5ae8e883f516ed
- Document Type :
- article
- Full Text :
- https://doi.org/10.3762/bjoc.19.59