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Bioavailability of iron measurement in two nutrients multiple solutions by in vitro and in vivo: a comparative methodology between methods

Authors :
Luciana Bueno
Juliana C. Pizzo
Osvaldo Freitas
Fernando Barbosa Junior
José Ernesto dos Santos
Julio Sergio Marchini
José Eduardo Dutra-de-Oliveira
Source :
Nutrición Hospitalaria, Vol 28, Iss 1, Pp 93-99 (2013)
Publication Year :
2013
Publisher :
Arán Ediciones, S. L., 2013.

Abstract

Objectives: The bioavailability of dietary iron present in a nutritional formulation may be evaluated by in vitro and in vivo methods since they provide for a cohesive line study and provided in the literature. The aim of this study was to evaluate the bioavailability of iron targeting a comparative analysis of two nutritional supplement formulations (A and B). Methods: For this study were using in vitro and in vivo methods, both described in the literature for availability of iron in an enteral feeding after ingestion supplement nutrition with much nutrients. Results: The results obtained by in vitro simulation of the human gastrointestinal tract were 0.70 ± 0.02 and 0.80 ± 0.01 % iron availability by formulations A and B. In vivo studies, as measured by the curves of serum iron in humans after ingestion of formulations allowed the calculation of coefficient of variation Δ < 0, indicating that there was a low absorption of iron. The bioavailability of iron as two multinutrients solutions obtained by in vitro and in vivo showed that there were comparisons of those methodologies used in this study.

Details

Language :
English, Spanish; Castilian
ISSN :
02121611
Volume :
28
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nutrición Hospitalaria
Publication Type :
Academic Journal
Accession number :
edsdoj.14f37cccf4c54916b841955b13021b76
Document Type :
article
Full Text :
https://doi.org/10.3305/nh.2013.28.1.5965