Changes in Systemic Hemodynamics in Hypertensive Patients with Diabetes Mellitus Type 2 Depending on the Type of Left Ventricular Remodeling

The main purpose of the study was to investigate the changes of systemic hemodynamics in patients with essential hypertension stage II in combination with type 2 diabetes, depending on the type of left ventricular remodeling. The research involved 150 patients aged 38 to 65 years old (average age was 53.7 ± 5.6 years). The main group consisted of 60 patients with essential hypertension stage II in combination with type 2 diabetes. The comparison groups consisted of 30 apparently healthy individuals, 30 patients with essential hypertension and 30 patients with type 2 diabetes of the same age. The ultrasound studies have shown that patients of the main group have more adverse types of myocardial remodeling with a predominance of eccentric hypertrophy and concentric remodeling. Accordingly, in the same group of patients, there are more severe violations of systemic hemodynamics with a significant decrease in stroke volume, systolic index against the background of high total peripheral vascular resistance and prevalence of eukinetic and hypokinetic types of systemic hemodynamics. The correlations with the main indicators of the intracardiac systemic hemodynamics confirm a single pathogenetic mechanism of the cardiovascular remodeling in patients with hypertension combined with type 2 diabetes.