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Antibacterial Inhibitor as an Expired Metoclopramide in 0.5M Phosphoric Acid

Authors :
Rana Afif Anaee
Majed Hameed Abd Al-Majeed
Shaimaa Alaa Naser
Mustafa M. Kathem
Omer Akram Ahmed
Source :
Al-Khawarizmi Engineering Journal, Vol 15, Iss 1 (2019)
Publication Year :
2019
Publisher :
Al-Khwarizmi College of Engineering – University of Baghdad, 2019.

Abstract

Expired drug Metoclopramide was investigated as an antibacterial corrosion inhibitor for carbon steel in 0.5M H3PO4 solution using the electrochemical method at 30oC and 60oC. The results showed that this drug is an efficient inhibitor for carbon steel and the efficiency reached to 82.244 % for 175 ppm at 30oC and 76.146% for 225 ppm at 60oC. The adsorption of drug on carbon steel surface follows Langmuir adsorption isotherm with small values of adsorption-desorption constant. The polarization plots revealed that Metoclopramide acts as mixed-type inhibitor. Some parameters of inhibition process were calculated and discussed. The surface morphology of the carbon steel specimens was analyzed using scanning electron microscope and energy dispersive X-ray analysis. Antibacterial activity of inhibitor was also tested. Fourier-transform infrared (FTIR) spectroscopy confirmed the inhibitive role of Metoclopramide drug.

Details

Language :
English
ISSN :
18181171 and 23120789
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Al-Khawarizmi Engineering Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.17cbca010494748bb8d7df27bb58744
Document Type :
article
Full Text :
https://doi.org/10.22153/kej.2019.08.002