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Continuous biomarker monitoring with single molecule resolution by measuring free particle motion

Authors :
Alissa D. Buskermolen
Yu-Ting Lin
Laura van Smeden
Rik B. van Haaften
Junhong Yan
Khulan Sergelen
Arthur M. de Jong
Menno W. J. Prins
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Various applications would benefit from the ability to continuously measure biomolecules. Here the authors describe a biosensing technology based on the free diffusion of biofunctionalized particles hovering over a sensor surface, which enables monitoring of analytes (pM-µM) over long timespans.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.197fd922aa491b90fadaf826fed6dd
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33487-3