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Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults.
- Source :
- PLoS ONE, Vol 12, Iss 5, p e0174435 (2017)
- Publication Year :
- 2017
- Publisher :
- Public Library of Science (PLoS), 2017.
-
Abstract
- Vitamin D insufficiency, defined as 25-hydroxyvitamin D (25(OH)D) levels < 75nmol/L is associated with cardio-metabolic dysfunction. Vitamin D insufficiency is associated with inflammation and fibrosis, but it remains uncertain whether these anomalies are readily reversible. Therefore, we aimed to determine the effects of vitamin D supplementation on markers of: 1) nitric oxide (NO) signaling, 2) inflammation, and 3) fibrosis, in healthy volunteers with mild hypovitaminosis.Healthy volunteers (n = 35) (mean age: 45 ± 11 years) with 25(OH)D levels
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 12
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- PLoS ONE
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.19ab38ebebcb4aa5af51c17f6ab9bded
- Document Type :
- article
- Full Text :
- https://doi.org/10.1371/journal.pone.0174435