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UNC-43/CaMKII-triggered anterograde signals recruit GABAARs to mediate inhibitory synaptic transmission and plasticity at C. elegans NMJs

Authors :
Yue Hao
Haowen Liu
Xian-Ting Zeng
Ya Wang
Wan-Xin Zeng
Kang-Ying Qian
Lei Li
Ming-Xuan Chi
Shangbang Gao
Zhitao Hu
Xia-Jing Tong
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

The pre-and postsynaptic communication is critical for faithful synaptic transmission and induction of synaptic plasticity. Here, the authors found that CaMKII functions at GABAergic neurons to recruit GABAARs by triggering anterograde signals.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1ad9750d46c34b75a84e37c98cb49c24
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-023-37137-0