Back to Search Start Over

Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

Authors :
Matteo Bassetti
Daniele R. Giacobbe
Antonio Vena
Cecilia Trucchi
Filippo Ansaldi
Massimo Antonelli
Vaclava Adamkova
Cristiano Alicino
Maria-Panagiota Almyroudi
Enora Atchade
Anna M. Azzini
Novella Carannante
Alessia Carnelutti
Silvia Corcione
Andrea Cortegiani
George Dimopoulos
Simon Dubler
José L. García-Garmendia
Massimo Girardis
Oliver A. Cornely
Stefano Ianniruberto
Bart Jan Kullberg
Katrien Lagrou
Clement Le Bihan
Roberto Luzzati
Manu L. N. G. Malbrain
Maria Merelli
Ana J. Marques
Ignacio Martin-Loeches
Alessio Mesini
José-Artur Paiva
Maddalena Peghin
Santi Maurizio Raineri
Riina Rautemaa-Richardson
Jeroen Schouten
Pierluigi Brugnaro
Herbert Spapen
Polychronis Tasioudis
Jean-François Timsit
Valentino Tisa
Mario Tumbarello
Charlotte H. S. B. van den Berg
Benoit Veber
Mario Venditti
Guillaume Voiriot
Joost Wauters
Philippe Montravers
Source :
Critical Care, Vol 23, Iss 1, Pp 1-7 (2019)
Publication Year :
2019
Publisher :
BMC, 2019.

Abstract

Abstract Background The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. Methods A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal candidiasis in European ICU project (EUCANDICU). Results During the study period, 570 episodes of ICU-acquired IC were observed, with a cumulative incidence of 7.07 episodes per 1000 ICU admissions, with important between-center variability. Separated, non-mutually exclusive cumulative incidences of candidemia and IAC were 5.52 and 1.84 episodes per 1000 ICU admissions, respectively. Crude 30-day mortality was 42%. Age (odds ratio [OR] 1.04 per year, 95% CI 1.02–1.06, p

Details

Language :
English
ISSN :
13648535
Volume :
23
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Critical Care
Publication Type :
Academic Journal
Accession number :
edsdoj.1bf8274562848d992e673991012b3c7
Document Type :
article
Full Text :
https://doi.org/10.1186/s13054-019-2497-3