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The Expression of CD38 ADP-ribosyl Cyclase Ectoenzyme in Immune Cells of Cardiac Surgical Patients
The Expression of CD38 ADP-ribosyl Cyclase Ectoenzyme in Immune Cells of Cardiac Surgical Patients
- Source :
- Acta Medica, Vol 51, Iss 1, Pp 31-35 (2008)
- Publication Year :
- 2008
- Publisher :
- Karolinum Press, 2008.
-
Abstract
- Background: This study was aimed at following the changes in the expression of CD38 ADP-ribosyl cyclase ectoenzyme on peripheral blood immune cells of patients undergoing cardiac surgical operations. Patients and Methods: The expression of CD38 on lymphoid and myeloid cells was determined by immunofluorescence and flow cytometry in forty cardiac surgical patients assigned to surgery either using (“on-pump”, n=20) or without the use (“off-pump”, n=20) of cardiopulmonary bypass. Results: There was a very rapid upregulation of CD38 expression in “on-pump” patients, becoming significant at declamping of aorta (p
- Subjects :
- Cardiac surgery
Immune cells
Activation
CD38
Expression
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 18059694 and 12114286
- Volume :
- 51
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Acta Medica
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1cb97cbe31cf47a2b92a1755b6e22756
- Document Type :
- article
- Full Text :
- https://doi.org/10.14712/18059694.2017.5