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The Expression of CD38 ADP-ribosyl Cyclase Ectoenzyme in Immune Cells of Cardiac Surgical Patients

The Expression of CD38 ADP-ribosyl Cyclase Ectoenzyme in Immune Cells of Cardiac Surgical Patients

Authors :
Martina Koláčková
Manuela Trojáčková Kudlová
Vladimír Lonský
Jiří Manďák
Pavel Kuneš
Karolína Jankovičová
Dana Vlášková
Ctirad Andrýs
Jan Krejsek
Source :
Acta Medica, Vol 51, Iss 1, Pp 31-35 (2008)
Publication Year :
2008
Publisher :
Karolinum Press, 2008.

Abstract

Background: This study was aimed at following the changes in the expression of CD38 ADP-ribosyl cyclase ectoenzyme on peripheral blood immune cells of patients undergoing cardiac surgical operations. Patients and Methods: The expression of CD38 on lymphoid and myeloid cells was determined by immunofluorescence and flow cytometry in forty cardiac surgical patients assigned to surgery either using (“on-pump”, n=20) or without the use (“off-pump”, n=20) of cardiopulmonary bypass. Results: There was a very rapid upregulation of CD38 expression in “on-pump” patients, becoming significant at declamping of aorta (p

Details

Language :
English
ISSN :
18059694 and 12114286
Volume :
51
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Acta Medica
Publication Type :
Academic Journal
Accession number :
edsdoj.1cb97cbe31cf47a2b92a1755b6e22756
Document Type :
article
Full Text :
https://doi.org/10.14712/18059694.2017.5