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Targeted proteomics identifies liquid-biopsy signatures for extracapsular prostate cancer

Authors :
Yunee Kim
Jouhyun Jeon
Salvador Mejia
Cindy Q Yao
Vladimir Ignatchenko
Julius O Nyalwidhe
Anthony O Gramolini
Raymond S Lance
Dean A Troyer
Richard R Drake
Paul C Boutros
O. John Semmes
Thomas Kislinger
Source :
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Publication Year :
2016
Publisher :
Nature Portfolio, 2016.

Abstract

Proteomic technologies are capable of identifying thousands of proteins in biological samples, but biomarker applications are lagging. Here the authors use Multiple Reaction Monitoring Mass Spectrometry to delineate peptide signatures that accurately distinguish between defined prostate cancer patient risk groups.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.1db668735dc049b6843a5ba098f31c1d
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms11906