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Screening of anti-oxidant and anti-bacterial metabolites from brown algae Turbinaria ornata for inhibits the multi-drug resistant P. aeruginosa
- Source :
- Journal of King Saud University: Science, Vol 32, Iss 8, Pp 3447-3453 (2020)
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- In this study, the anti-oxidant and anti-bacterial activity of marine brown algae Turbinaria ornata (T. ornate) extract was purified by soxhlet apparatus method. The invitro studies of total anti-oxidant activity and DPPH hydroxyl scavenging activity assays were suggested that the T. ornata extract has more anti-oxidant activity. Agar well diffusion and minimum inhibition concentration results were exhibited excellent inhibition effect of T. ornata extract against P. aeruginosa at 300 µg/mL concentration. The time-dependent bacterial inhibition assay was also confirmed the 300 µg/mL concentration at 24 h. Further, the increased death cells and extracellular shape alteration results were observed by confocal laser scanning electron microscope and scanning electron microscope. Therefore, our result was suggested that the T. ornata extract as a promising anti-bacterial agent for multi-drug resistant P. aeruginosa.
Details
- Language :
- English
- ISSN :
- 10183647
- Volume :
- 32
- Issue :
- 8
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of King Saud University: Science
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1f991af75cb24422aace21a0b4ca89eb
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jksus.2020.10.005