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A patient with hereditary transthyretin amyloidosis involving multiple cranial nerves due to a rare p.(Phe84Ser) variant

Authors :
Yan Xian-rang
Hong Ming-fan
Zhou Zhi-hua
Liu Ai-qun
Peng Zhong-xing
Wu Wei-feng
Jing Cheng
Lin Jia-xiu
Long Ying
Yu Qing-yun
Source :
Translational Neuroscience, Vol 13, Iss 1, Pp 116-119 (2022)
Publication Year :
2022
Publisher :
De Gruyter, 2022.

Abstract

We report a 30-year-old man involving gastrointestinal symptoms, vitreous opacity, and multiple cranial neuropathies. Transthyretin-related hereditary amyloidosis genetic testing revealed a rare c.251T > C variant p.(Phe84Ser). Only four cases with this variant have been reported before.

Details

Language :
English
ISSN :
20816936 and 20220219
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Translational Neuroscience
Publication Type :
Academic Journal
Accession number :
edsdoj.20b8e3a35f8462fa5d57ce40015fc99
Document Type :
article
Full Text :
https://doi.org/10.1515/tnsci-2022-0219