Back to Search
Start Over
Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Mitochondria power the beating heart. Here, Donnarumma et al. show that loss of the inner mitochondrial membrane protein MTFP1 in cardiomyocytes reduces bioenergetic efficiency and cell death resistance leading to heart failure in mice.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.21337b4dba243f385e7018fb31873cd
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-34316-3