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Yolk sac macrophage progenitors traffic to the embryo during defined stages of development

Authors :
C. Stremmel
R. Schuchert
F. Wagner
R. Thaler
T. Weinberger
R. Pick
E. Mass
H. C. Ishikawa-Ankerhold
A. Margraf
S. Hutter
R. Vagnozzi
S. Klapproth
J. Frampton
S. Yona
C. Scheiermann
J. D. Molkentin
U. Jeschke
M. Moser
M. Sperandio
S. Massberg
F. Geissmann
C. Schulz
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Tissue-resident macrophages are derived from yolk sac progenitors but how and when these progenitors enter is unclear. Here the authors use fate mapping and intravital microscopy to track the movement of resident macrophage precursors from the yolk sac to fetal tissues during development.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2245da82b8e410380e13c722cd3ce70
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-02492-2