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Factor VIII-Fc Activates Natural Killer Cells via Fc-Mediated Interactions With CD16

Authors :
H.A. Daniel Lagassé
Louis B. Hopkins
Wojciech Jankowski
Marc G. Jacquemin
Zuben E. Sauna
Basil Golding
Source :
Frontiers in Immunology, Vol 12 (2021)
Publication Year :
2021
Publisher :
Frontiers Media S.A., 2021.

Abstract

The most challenging complication associated with Factor VIII (FVIII) replacement therapy is the development of neutralizing anti-drug antibodies, or inhibitors, which occur in 23-35% of severe (FVIII level

Details

Language :
English
ISSN :
16643224
Volume :
12
Database :
Directory of Open Access Journals
Journal :
Frontiers in Immunology
Publication Type :
Academic Journal
Accession number :
edsdoj.22873ee2cdf4676ba4a6bbfc337d8a3
Document Type :
article
Full Text :
https://doi.org/10.3389/fimmu.2021.692157