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Myelomatous Pleural Effusion : Case report and review of the literature

Authors :
Khalil Al-Farsi
Ibrahim Al-Haddabi
Nafla Al-Riyami
Rashid Al-Sukaiti
Salam Al-Kindi
Source :
Sultan Qaboos University Medical Journal, Vol 11, Iss 2, Pp 259-264 (2011)
Publication Year :
2011
Publisher :
Sultan Qaboos University, 2011.

Abstract

Plasma cell myeloma is an uncommon disease which, besides primarily involving the bone marrow, has a tendency to involve other organs thus presenting with different clinical manifestations. While pleural effusions are infrequent in this disease, true myelomatous pleural effusions are extremely rare. We report the case of a middle-aged Omani man with relapsed plasma cell myeloma who developed bilateral pleural effusions. The diagnosis of myelomatous pleural effusion was made by finding many abnormal plasma cells as well as a high level of a monoclonal protein (IgG κ) in the pleural fluid. In spite of a good initial response to therapy, the patient had progressive disease and died 6 months later with bacterial sepsis. We present a review of the literature that indicates the rarity of such a manifestation and its association with poor prognosis and short survival.

Details

Language :
English
ISSN :
2075051X and 20750528
Volume :
11
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Sultan Qaboos University Medical Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.2440416d5b0a4f0590d8a418144f28f2
Document Type :
article