Back to Search Start Over

Twenty-four-year-old patient with heart failure after myocarditis. Results of quadruple therapy: a case report

Authors :
V. N. Larina
I. K. Skiba
T. A. Romanova
A. S. Skiba
Source :
Российский кардиологический журнал, Vol 28, Iss 3 (2023)
Publication Year :
2023
Publisher :
«FIRMA «SILICEA» LLC, 2023.

Abstract

Introduction. The data of epidemiological studies indicate maintaining high prevalence of heart failure (HF) and an unfavorable prognosis for such patients, which creates the need to change the treatment approach. A feature of the case presented is the young age of the patient and a significant effect that was achieved with quadruple therapy for HF with reduced ejection fraction (EF) after myocarditis.Short description. A three-year follow-up of a patient with HFrEF was carried out. In 2019, at the age of 21, the patient had acute myocarditis, diagnosed according to magnetic resonance imaging. The outcome was postmyocarditis cardiosclerosis, complicated by HFrEF. She had two episodes of HF decompensation, followed by hospitalizations in a cardiology hospital. During the treatment, a quadruple therapy was initiated (angiotensin receptor-neprilysin inhibitor, beta-blocker, mineralocorticoid receptor antagonist, sodium-glucose cotransporter 2 inhibitor), against which a significant improve was noted in the form of decrease in congestion symptoms, natriuretic peptide level from 1956 to 501,4 pg/ml, an increase in LVEF from 33% to 39%. The patient is currently on the waiting list for a donor heart transplant.Conclusion. The case report focuses on the complexity of not only the timely diagnosis of myocarditis, but also the treatment of its consequences. The appointment of quadruple therapy for a patient with HF after myocarditis has improved the patient’s clinical condition before heart transplantation. However, this approach needs to be confirmed in a larger number of patients.

Details

Language :
Russian
ISSN :
15604071 and 26187620
Volume :
28
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Российский кардиологический журнал
Publication Type :
Academic Journal
Accession number :
edsdoj.26460202668481eacd7305091920446
Document Type :
article
Full Text :
https://doi.org/10.15829/1560-4071-2023-5341