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Trajectory of immune evasion and cancer progression in hepatocellular carcinoma

Authors :
Phuong H. D. Nguyen
Martin Wasser
Chong Teik Tan
Chun Jye Lim
Hannah L. H. Lai
Justine Jia Wen Seow
Ramanuj DasGupta
Cheryl Z. J. Phua
Siming Ma
Jicheng Yang
Sheena D/O Suthen
Wai Leong Tam
Tony K. H. Lim
Joe Yeong
Wei Qiang Leow
Yin Huei Pang
Gwyneth Soon
Tracy Jiezhen Loh
Wei Keat Wan
Chung Yip Chan
Peng Chung Cheow
Han Chong Toh
Alfred Kow
Yock Young Dan
Juinn Huar Kam
Shridhar Iyer
Krishnakumar Madhavan
Alexander Chung
Glenn K. Bonney
Brian K. P. Goh
Naiyang Fu
Victor C. Yu
Weiwei Zhai
Salvatore Albani
Pierce K. H. Chow
Valerie Chew
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

In order to design cancer immune therapies, it is important to understand how tumours evade the immune response that is mounted against them. Authors here analyse the distribution and properties of immune cells in hepatocellular carcinoma and describe a progressive tumour-immune co-evolution programme from early to late stage cancer.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2648047cd2d74e93ad29e2f0557f8fa3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29122-w