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Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex
- Source :
- Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
- Publication Year :
- 2022
- Publisher :
- Nature Portfolio, 2022.
-
Abstract
- Unwanted RNA transcripts are targeted for degradation by nuclear complexes such as MTREC/PAXT. Here, the authors structurally and functionally characterized three interfaces of the scaffold protein Red1, providing mechanistic insights into conserved features of MTREC/PAXT architecture.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 13
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.277482d7e23417582ce5dd3cf5d0971
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-022-32542-3