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Brown adipose tissue monocytes support tissue expansion

Authors :
Alexandre Gallerand
Marion I. Stunault
Johanna Merlin
Hannah P. Luehmann
Deborah H. Sultan
Maria M. Firulyova
Virginie Magnone
Narges Khedher
Antoine Jalil
Bastien Dolfi
Alexia Castiglione
Adelie Dumont
Marion Ayrault
Nathalie Vaillant
Jérôme Gilleron
Pascal Barbry
David Dombrowicz
Matthias Mack
David Masson
Thomas Bertero
Burkhard Becher
Jesse W. Williams
Konstantin Zaitsev
Yongjian Liu
Rodolphe R. Guinamard
Laurent Yvan-Charvet
Stoyan Ivanov
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and show that monocytes contribute to brown adipose tissue expansion.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.27f3045057046fd93f4d2ad42eab91a
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-25616-1