Back to Search Start Over

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

Authors :
Lei Zhu
Rob W. van der Pluijm
Michal Kucharski
Sourav Nayak
Jaishree Tripathi
Nicholas J. White
Nicholas P. J. Day
Abul Faiz
Aung Pyae Phyo
Chanaki Amaratunga
Dysoley Lek
Elizabeth A. Ashley
François Nosten
Frank Smithuis
Hagai Ginsburg
Lorenz von Seidlein
Khin Lin
Mallika Imwong
Kesinee Chotivanich
Mayfong Mayxay
Mehul Dhorda
Hoang Chau Nguyen
Thuy Nhien Thanh Nguyen
Olivo Miotto
Paul N. Newton
Podjanee Jittamala
Rupam Tripura
Sasithon Pukrittayakamee
Thomas J. Peto
Tran Tinh Hien
Arjen M. Dondorp
Zbynek Bozdech
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Transcriptomic analysis of isolates from the malaria parasite (Plasmodium falciparum) in the Greater Mekong Subregion of Southeast Asia identifies gene expression patterns that are correlated with resistance to a common anti-malaria drug, artemisinin.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.2819f6d4f533428085849ed66f62dc4e
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03215-0