Back to Search Start Over

Cdk5 activation promotes Cos-7 cells transition towards neuronal-like cells

Authors :
Bao Li
Lan Xiao-Mei
Zhang Guo-Qing
Bao Xi
Li Bo
Ma Dan-Na
Luo Hong-Yan
Cao Shi-Lu
Liu Shun-Yao
Jing E
Zhang Jian-Zhong
Zheng Ya-Li
Source :
Translational Neuroscience, Vol 14, Iss 1, Pp 8001-12 (2023)
Publication Year :
2023
Publisher :
De Gruyter, 2023.

Abstract

Cyclin-dependent kinase 5 (Cdk5) activity is specifically active in neurogenesis, and Cdk5 and neocortical neurons migration related biomarker are expressed in Cos-7 cells. However, the function of Cdk5 on the transformation of immortalized Cos-7 cells into neuronal-like cells is not clear.

Details

Language :
English
ISSN :
20816936
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Translational Neuroscience
Publication Type :
Academic Journal
Accession number :
edsdoj.29db9f92ffb430197d01370ef57adfc
Document Type :
article
Full Text :
https://doi.org/10.1515/tnsci-2022-0318