Back to Search
Start Over
Analysis of a Serious Adverse Reaction of Pulmonary Fibrosis Caused by Dronedarone
- Source :
- Current Therapeutic Research, Vol 100, Iss , Pp 100743- (2024)
- Publication Year :
- 2024
- Publisher :
- Elsevier, 2024.
-
Abstract
- Objective: This study aims to analyze a severe adverse reaction of pulmonary fibrosis induced by dronedarone hydrochloride tablets, and to provide a reference for clinical rational medication through drug precautions. Methods: A case of pulmonary fibrosis induced by dronedarone hydrochloride tablets, along with related literature was retrospectively analyzed. Results: Patients over 65 years old with a history of exposure to amiodarone may increase the incidence of pulmonary toxicity induced by dronedarone, and dronedarone should not be selected as a substitute treatment drug for patients with amiodarone-induced pulmonary toxicity. Conclusions: It is recommended that clinicians monitor the diffusion capacity of carbon monoxide and lung ventilation function of patients before and after using dronedarone for treatment. For patients with a history of amiodarone exposure, intermittent monitoring of chest X-rays and lung function is necessary. If lung function decreases, dronedarone should be immediately discontinued.
Details
- Language :
- English
- ISSN :
- 0011393X
- Volume :
- 100
- Issue :
- 100743-
- Database :
- Directory of Open Access Journals
- Journal :
- Current Therapeutic Research
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2a55cb111d544d6c9d1a24ba2b3c43b3
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.curtheres.2024.100743