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Pan-urologic cancer genomic subtypes that transcend tissue of origin

Authors :
Fengju Chen
Yiqun Zhang
Dominick Bossé
Aly-Khan A. Lalani
A. Ari Hakimi
James J. Hsieh
Toni K. Choueiri
Don L. Gibbons
Michael Ittmann
Chad J. Creighton
Source :
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Publication Year :
2017
Publisher :
Nature Portfolio, 2017.

Abstract

Urological cancers have disparate tissues and cells of origin but share many molecular features. Here, the authors use multidimensional and comprehensive molecular characterization to classify urological cancers into nine major genomic subtypes, highlighting potential therapeutic targets.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
8
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2a8db6a9c87c4e43a1566658a963a777
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-017-00289-x