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Insights into the antimicrobial effects of ceritinib against Staphylococcus aureus in vitro and in vivo by cell membrane disruption
- Source :
- AMB Express, Vol 12, Iss 1, Pp 1-15 (2022)
- Publication Year :
- 2022
- Publisher :
- SpringerOpen, 2022.
-
Abstract
- Key points Ceritinib showed fierce lethality to the planktonic and persistent S. aureus. Ceritinib were highly effective in MRSA biofilm eradication and inhibition. The bactericidal mechanisms of ceritinib were showed by membrane breaking and ROS activation.
Details
- Language :
- English
- ISSN :
- 21910855
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- AMB Express
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2ac703962c4307b8c03d2b52a3809c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s13568-022-01492-w